Alien Soldier (エイリアンソルジャー?) is a side-scrolling run and gun video game developed by Treasure for the Sega Mega Drive. The game was released in Japan and Europe, but not physically in the US (one of the few to be released in this pattern), but it can be rather expensive due to its rarity in either region. The game was playable in America on the Sega Channel cable service and has been reissued for PlayStation 2 as part of the Sega Ages Treasure Box disc. The Sega Ages version, whose disc also includes Treasure's Gunstar Heroes and Dynamite Headdy, exceeds the Mega Drive's intrinsic sprite display limit, which eliminates slowdowns or missing graphics during busy scenes (e.g. boss fights with many explosions). Also, the player can select either the sprite-based pixelated graphics of the original game or a new mode that uses certain filters to produce a high-resolution look. The game was re-released again on the Nintendo Wii's Virtual Console download service in Japan on October 9, 2007, in Europe on November 2, 2007, and North America debut on November 5, 2007. The game is listed in Guinness World Records Gamers Edition 2010 under the category "Most boss battles in a run and gun game". The catchphrases seen on the title screen, "FOR MEGADRIVERS CUSTOM" and "VISUALSHOCK! SPEEDSHOCK! SOUNDSHOCK! NOW IS TIME TO THE 68000 HEART ON FIRE!", describe the game's technical prowess for the Mega Drive hardware, at the core of which is the Motorola 68000 CPU.

Altered Beast (獣王記, Jūōki?, lit. "Beast King's Chronicle") is a 1988 beat 'em up arcade game developed and manufactured by Sega. The game is set in Ancient Greece, and follows a centurion who is resurrected by Zeus to rescue his daughter Athena, and to do so becomes able to turn into beasts such as the werewolf with the use of power-ups. After its initial arcade release, it was ported to several home video game consoles and home computers, including the Sega Mega Drive and Sega Genesis, for which it was a pack-in game. This ultimately led to the Sega Genesis being shipped with Sonic the Hedgehog instead. The primary designer was Makoto Uchida, also responsible for the creation of Golden Axe.

Another World, also known as Out of This World in North America and Outer World (アウターワールド Autā Wārudo?) in Japan, is a 1991 cinematic platformer action-adventure game designed by Éric Chahi for Delphine Software. The game tells a story of Lester, a young scientist who, as a result of an experiment gone wrong, finds himself in a dangerous alien world where he is forced to fight for his survival. Originally developed for the Amiga and Atari ST and later released for the Apple IIGS and DOS platforms, the game was widely ported to other contemporary systems. Later efforts resulted in several game engine recreations for the game that permitted it to run on modern computers, consoles and mobile phones. In 2006, Chahi independently released a 15th Anniversary Edition for Windows which allowed the game to be played on modern computers with original or enhanced visuals; following up in 2011 for its 20th anniversary, ports of the game were prepared for iOS and Android based devices. Another World was highly innovative in its use of cinematic effects in both real-time and cutscenes, which granted the game praise amongst critics and commercial success. It also influenced a number of other video games and designers.

Ariel the Little Mermaid is a video game that was developed by Blue Sky software and released for the Sega Genesis in 1992.