Alien Soldier (エイリアンソルジャー?) is a side-scrolling run and gun video game developed by Treasure for the Sega Mega Drive. The game was released in Japan and Europe, but not physically in the US (one of the few to be released in this pattern), but it can be rather expensive due to its rarity in either region. The game was playable in America on the Sega Channel cable service and has been reissued for PlayStation 2 as part of the Sega Ages Treasure Box disc. The Sega Ages version, whose disc also includes Treasure's Gunstar Heroes and Dynamite Headdy, exceeds the Mega Drive's intrinsic sprite display limit, which eliminates slowdowns or missing graphics during busy scenes (e.g. boss fights with many explosions). Also, the player can select either the sprite-based pixelated graphics of the original game or a new mode that uses certain filters to produce a high-resolution look. The game was re-released again on the Nintendo Wii's Virtual Console download service in Japan on October 9, 2007, in Europe on November 2, 2007, and North America debut on November 5, 2007. The game is listed in Guinness World Records Gamers Edition 2010 under the category "Most boss battles in a run and gun game". The catchphrases seen on the title screen, "FOR MEGADRIVERS CUSTOM" and "VISUALSHOCK! SPEEDSHOCK! SOUNDSHOCK! NOW IS TIME TO THE 68000 HEART ON FIRE!", describe the game's technical prowess for the Mega Drive hardware, at the core of which is the Motorola 68000 CPU.

Awesome Possum... Kicks Dr. Machino's Butt is a video game created by Tengen for the Sega Mega Drive/Genesis that was released in the early 1993.

Champions World Class Soccer (チャンピオンズ ワールドクラスサッカー?) is a football (soccer) video game released on the Sega Genesis and Super Nintendo Entertainment System in 1993 and 1994, developed by Park Place Productions and published by Flying Edge and Acclaim. The British release featured a picture of Welsh international Ryan Giggs on the game box. The German featured Sepp Maier, and the French featured Paris Saint-Germain. Modes of play included in the game are Exhibition Match (one player or two players) and Tournament Mode. Progress through the tournament can be saved via a password given at the end of each match. There are also options to turn fouls and offsides on or off, as well as selecting the amount of time allowed for the match to be played in.

Chip McCallahan in Sonic the Hedgehog 2 is a Sonic 2 hack created by MainMemory. It replaces Sonic the Hedgehog and Tails with Chip McCallahan, the main character in Chip's Challenge. Chip can't run fast, roll or jump high, and rings do not protect him from damage. When you die, you will get one of the death messagesfrom Chip's Challenge, and the level will restart with no decrease in your life count.